GNE MYOPATHY AYURVEDIC TREATMENT, SYMPTOMS, CAUSES & MORE
ABSTRACT
GNE myopathy is a skeletal muscle primarily affecting genetic disease. Other names for it include distal myopathy with rimmed vacuoles, IBM2, HIBM, and Nonaka myopathy. The condition affects both men and women equally, with the earliest symptoms appearing between the ages of 20 and 40. A decrease in grip strength, frequent balance problems, and progressive muscular weakness are all signs of this condition. The goal of therapy is symptom control because there is currently no cure for the disorder. On the other hand, ayurveda may help in the treatment of this condition. So let’s have a look!
INTRODUCTION
The genetic muscle condition known as GNE myopathy is caused by a faulty gene. It is an uncommon illness that affects around one person in a million people worldwide. Legs and arms experience atrophy and muscle weakening as a result. Young adults are typically when symptoms first appear, but some people have reported a later onset. Foot drop is typically accompanied initially by an increase in tripping and a steppage stride. Over time, the issue gets worse, leading to weakening of the hands and shoulder muscles, trouble getting up from a sitting position or climbing stairs, and proximal leg muscular weakness.
CAUSES
The GNE gene, which produces the enzyme glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase, is altered (mutated), resulting in GNE myopathy. Infection, muscular damage, medicines, irregular electrolytes, and thyroid problems are among more factors.
SYMPTOMS
Symptoms associated with GNE Myopathy are as follows:
- Progressively losing muscle
- Tibialis anterior muscle weakening causing bilateral foot dips
- Disturbed gait and repeated falls
- Decreased stability
- Difficulty with routine daily physical tasks like sprinting, climbing stairs, or maintaining a strong hold on an object
- Within 10 to 20 years of the onset, the patient loses all voluntary movement in their lower limbs, with the exception of their quadriceps muscles.
DISORDERS WITH SIMILAR SYMPTOMS
Clinically, the diagnosis could be mistaken for other illnesses such as Charcot-Marie-Tooth disease, various distal myopathies, limb-girdle muscular dystrophy, or spinal muscular atrophy.
RISK FACTORS
- Infections
- Endocrine problems
- Examples of autoimmune disorders include thyroiditis, scleroderma, and myasthenia gravis.
- Toxin exposure from substances like insecticides and flame retardants
- Among the medications utilised include long-term corticosteroids and antihistamines.
- Lacking in vitamins
- Examples of metabolic illnesses include problems of lipid and glycogen storage.
MODERN SCIENCE TREATMENT
Treatment focuses on postponing the whole loss of muscle strength and mobility because a complete solution has not yet been discovered. The illness process can be sped up by excessive or insufficient use. The ideal everyday mobility of the muscles combined with periodic physical therapy can prevent muscular wasting. Although Enzyme Replacement Therapy has demonstrated a slight but favourable impact on muscle strength, due to the effect’s tiny to inconsequential size, the study was abandoned.
DIAGNOSIS OF GNE MYOPATHY
- MRI
- Muscle Biopsy
- Genetic testing
AYURVEDIC OVERVIEW
In Ayurveda, it can be associated with Mamsa-shosha, which occurs due to an imbalance in dosha and dhatus (the main elements that control the body). Kapha is weak and causes ama formation in the body by blocking the digestive system. Since Kapha and Amma have similar properties, they weaken Vata energy by blocking the Srotas (channel). Vata is damaged and causes depletion of the area it affects. Additionally, Dhatwagni (metabolism), which is responsible for metabolism, decreases in terms of Dhatu (vital elements) which also leads to mamsa (muscle) loss.
CAUSES OF SHOSHA
- Vrana Janya shosha – ulcers
- Adhwagamana janya shosha – too much walking
- Urahkshata janya shosha – chest injury
- Shoka janya shosha – overwhelming sadness
- Vyavaya janya shosha – extreme fatigue
- Vyayam janya shosha – overly active exercise
- Vardhakya janya shosha – ageing, old age impact
HERBS THAT ARE USEFUL IN GNE MYOPATHY
- Guggul
- Gokshura
- Triphala
- Ashwagandha
- Bala
- Musta
- Arjuna
- Guduchi
PANCHKARMA
- Sarvanga Dhara
- Abhyanga
- Basti
- Sashtika Shali Pinda Sweda
YOGA RECOMMENDATION
- Tadasana
- Gomukhasana
- Parvatasana
- Bhujangasana
- Suryanamsakara
HERBAL REMEDIES FOR GNE MYOPATHY BY PLANET AYURVEDA
The well-known Ayurvedic pharmaceutical distributor Planet Ayurveda has a presence all over the world. All of our meds are absolutely safe to take and chemical-free. To guarantee that the medicines we create are of the greatest quality, we meticulously obtain all of the drugs that are used. To make your experience with GNE Myopathy easier than ever, all of the medicines we suggest for this ailment have been carefully chosen by our most reputable physicians. Your body will be able to retain muscular function for a lot longer thanks to these drugs.
PRODUCT LIST
- Ashwagandha Ghrit
- Musli Strength Capsules
- Boswellia Curcumin
- Yograj Guggul
- Atirasadi Churna
- Rasraj Ras
- Bala Ashwagandha Oil
PRODUCT DESCRIPTION
1. ASHWAGANDHADI GHRIT
This is a polyherbal ghrit that is made up of Go Dugdha (Cow Ghee), Ashwagandha (Withania somnifera), etc. It can be used to treat general weakness, sleeplessness, and neurological ailments. It works well for joint issues, arthritis of any kind, tiredness, stiffness in the neck or back, and muscular fatigue. Additionally, it relieves stress and anxiety. A few of the properties of go dugdha include Pavitra (Sacred), Pathya (clears obstructions), Balya (Tonic), Hridya (Cardio tonic), Rasayana (Vitalizer), Tridosha (Vata, Pitta, and Kapha), and Pushtikara (Nourishing).
Dosage: 1 teaspoon with warm water, two times a day.
2. MUSLI STRENGTH CAPSULES
These polyherbal capsules are made up of Gokshura (Tribulus terrestris), etc. It helps to improve the blood’s circulation of growth hormone. In order to lessen the consequences of GNE myopathy, this promotes the growth and strengthening of muscles. Gokshura may aid in lowering discomfort and swelling. Musli has anti-cancer, aphrodisiac and immunomodulatory effects.
Dosage: 1 capsule, two times a day.
3. BOSWELLIA CURCUMIN
Polyherbal capsules are a perfect combination of Curcumin (Curcuma longa) and Shallaki (Boswellia serrata). Curcumin has been utilised to treat a range of inflammatory illnesses and chronic diseases because of its antioxidant and anti-inflammatory properties. Boswellia is helpful in treating inflammation, swelling, etc. These capsules have a high antioxidant content that helps joints move freely and a neuroprotective action that helps keep the cardiovascular system healthy. It is used to treat various kinds of joint pain because it contains anti-inflammatory qualities.
Dosage: 2 capsules, two times a day.
4. YOGRAJ GUGGUL
Chitraka (Plumbago zeylancia), Yavani (Trachyspermum ammi), Devadaru (Cedrus deodara), Yavagraja (Hordeum vulgare), Patra (Cinnamomum zeylanicum), and many more. It is mostly used for conditions that affect the bone marrow, joints, and bones.
Dosage: 2 tablets, two times a day.
5. ATIRASADI CHURNA
This polyherbal churan is made up of Kali musli (Curculigo orchioides), Gokshura (Tribulus terrestris), Akarkara (Anacyclus pyrethrum), Kesar (Crocus sativus), and many more. It aids in lowering energy levels, stress, and worry. It aids in calming the vata doshas. The kali musli’s Rasayana characteristics fortify the body and promote the growth of a robust immune system. Additionally, the high antioxidant effect of this herbal remedy slows the ageing process and encourages the regeneration of new skin cells.
Dosage: 1 teaspoon two times per day with warm milk.
6. RASRAJ RAS
These are polyherbal tablets that are made up of Vjgandha (Withania somnifera), Jatikosh (Myristica fragrans), Ksheera kakoli (Fritillaria roylei), and many more. It has analgesic, inflammatory-reducing, antioxidant, and immune-modulating effects. It should be avoided during pregnancy and lactating phase of mothers.
Dosage: 1 tablet, two times a day, after meals, and chew it.
7. BALA ASHWAGANDHA OIL
This is a polyherbal oil that is made up of Ashwagandha (Withania somnifera), Bala (Sida cordifolia), and many more. The oil’s revitalising properties aid in nerve toning, nerve conduction improvement, and muscular relaxation. It works by gently massaging the muscles to help them relax.
Application: External application.
CONCLUSION
GNE myopathy, also known as hereditary inclusion body myopathy (HIBM), or Nonaka myopathy, is an uncommon autosomal recessive muscle disease characterised by progressive skeletal muscular atrophy. These herbal combinations may be used to counteract the side effects of long-term allopathic treatments that cause GNE Myopathy. due to the ineffectiveness of allopathic medicine. To get a genuine Ayurvedic product, start with Planet Ayurveda. For the treatment, you can schedule online video consultation with Planet Ayurveda Mohali.
Dr. Vikram Chauhan
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