ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is a term used to describe a diverse set of juvenile autosomal recessive diseases that affect bile production and manifest as cholestasis of hepatocellular origin. People with conditions like portal hypertension, hepatosplenomegaly, jaundice, or acute itching are specifically targeted. This illness primarily results in cirrhosis and an urgent need for a liver transplant. Progressive…
Abstract Sarcoidosis is a multisystem disease which has non-caseating granulomas found in the affected organs. The liver is the major organ of vertebrates and is helpful for the detoxification and synthesis of protein which is necessary for digestion and growth of the individual. The liver is the accessory organ for digestion which produces bile and is useful in the breakdown…