ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is a term used to describe a diverse set of juvenile autosomal recessive diseases that affect bile production and manifest as cholestasis of hepatocellular origin. People with conditions like portal hypertension, hepatosplenomegaly, jaundice, or acute itching are specifically targeted. This illness primarily results in cirrhosis and an urgent need for a liver transplant. Progressive…
Abstract Chylous ascites is a rare condition. Some three decades back, chylous ascites were reported as 1 in 20,000 cases. However, now the incidence of chylous ascites has increased. It is believed to have increased due to increase in the survival rate of patients with cancer and excessive surgical intervention such as laparoscopic surgery and transplantation. In this article, let…
Jaundice is caused by a build-up of a substance called ‘bilirubin’ in the blood and tissues of the body. Jaundice is characterized by yellow color of the skin, mucus membranes and eyes. The yellow coloring comes from bilirubin which is a by-product of old red blood cells. In medical terms, bilirubin is a waste product that is produced when red…
Abstract The liver is the largest internal and most metabolically complex organ in human beings. It performs numerous and different chemical functions including fighting off infection, neutralizing toxins, manufacturing proteins and hormones, controlling blood sugar and clotting of blood. Liver problems can prevent the liver from performing its vital functions normally. Some common liver problems include infection due to viruses…
ABSTRACT Jaundice is also known as icterus that presents yellowing of the skin and eyes. This is caused by hyperbilirubinemia (an excess of bilirubin in the blood). Body fluid may also be yellowish tinge. Bilirubin is a yellow pigment that is formed by the breakdown of dead blood cells in the liver. Many health babies have jaundice within a week…