ABSTRACT Crigler Najjar syndrome type 1 is a hereditary disorder that results in hepatic bilirubin conjugation causing severe neonatal unconjugated hyperbilirubinemia due to certain mutations in the gene leading to fatal outcomes for the infant. Due to hyperbilirubinemia there occurs bilirubin encephalopathy or kernicterus that is a severe form of brain damage leading to deafness, hypertonia, lethargy and oculomotor palsy….