Abstract Scleroderma is the disease of connective issues that involves fibrosis of tissues, vasculopathy, and abnormal functioning of the immune system. However many patients of scleroderma get affected with other connective tissue diseases as well and that is termed as Scleroderma overlap syndrome. This article is all about the Scleroderma-polymyositis overlap syndromes, causes, signs and symptoms, diagnosis and herbal treatment…